← BlogJune 28, 2026

How to Make the Perfect Greek Yogurt Stuffed Chicken Breast

Mediterranean · Medium · 45 min · 2 servings

Gluten-FreeLow-Carb
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Greek Yogurt Stuffed Chicken Breast

Chicken breasts stuffed with a creamy Greek yogurt and spinach filling offer an impressive boost of protein at over 50g per serving. The yogurt melts into a tangy, rich sauce inside the chicken as it bakes to perfection.

Why this recipe works

This Greek Yogurt Stuffed Chicken Breast recipe has been crafted to deliver restaurant-quality results in your home kitchen. At just 45 minutes from start to finish, it fits perfectly into a busy schedule without sacrificing flavor. Each serving comes in at 390 calories with 52g of protein, making it a balanced choice for any meal.

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What you will need

This recipe uses 6 simple ingredients that you can find at any grocery store:

  • 2 whole large chicken breasts
  • 0.75 cup plain nonfat Greek yogurt
  • 1 cup fresh baby spinach chopped
  • 2 cloves garlic minced
  • 0.5 tsp smoked paprika
  • 1 tsp salt and black pepper

Step by step instructions

Step 1: Preheat and Prepare the Filling

Preheat your oven to 400 degrees Fahrenheit. In a bowl, mix together Greek yogurt, chopped spinach, minced garlic, paprika, salt, and pepper until fully combined into a thick, creamy filling.

Step 2: Butterfly the Chicken

Using a sharp knife, carefully slice each chicken breast horizontally through the thickest part without cutting all the way through, creating a pocket. Season the outside of both breasts with salt and paprika.

Step 3: Stuff and Seal the Chicken

Spoon equal amounts of the yogurt spinach filling into each chicken pocket. Secure the opening with two or three toothpicks to prevent the filling from spilling out during baking.

Step 4: Bake Until Cooked Through

Place the stuffed chicken breasts in a lightly greased baking dish and bake at 400 degrees Fahrenheit for 28 to 30 minutes until the internal temperature reaches 165 degrees Fahrenheit. Remove toothpicks before serving.

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Easy substitutions

Missing an ingredient? Here are some swaps that work perfectly:

  • plain nonfat Greek yogurt → low-fat cream cheese for a richer filling
  • fresh baby spinach → frozen spinach that has been thawed and squeezed dry

Common mistakes to avoid

Watch out for these pitfalls that can affect your results:

  • Cutting the pocket too deep and slicing through the chicken completely which causes the filling to leak out entirely during baking
  • Overstuffing the pocket which forces the filling out and leaves the inside of the chicken undercooked

Nutrition facts

Per serving: 390 calories, 52g protein, 6g carbs, 14g fat, 1g fiber.

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